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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6796 | CB-5083 | CB5083,CB 5083 | p97 |
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM). | |||
T3124 | Carbendazim | Bavistin,Carbendazole,Mercarzole | Antifungal |
Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec... | |||
T9430 | Venadaparib | NOV140101,IDX-1197 | PARP |
Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the... | |||
T7318 | Elimusertib | BAY-1895344 | ATM/ATR |
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target... | |||
T13044 | Mevociclib | SY-1365 | CDK |
Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors. | |||
T2325 | Neratinib | HKI-272 | EGFR , HER |
Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively. | |||
T26978 | CEP-40125 | RXDX-107 | DNA Alkylation |
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors. | |||
T2619 | CH5132799 | PI3K , mTOR | |
CH5132799 has been used in trials studying the treatment of Solid Tumors. | |||
T1601 | Lomustine | CCNU,NSC 79037 | Apoptosis , Others , DNA Alkylator/Crosslinker , DNA Alkylation , Autophagy |
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors. | |||
T7708 | DL-Buthionine-(S,R)-sulfoximine | Butionine sulfoximine,NSC 381100,D,L-Buthionine-(S,R)-sulfoximine | Others , Ferroptosis |
DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors. | |||
T73425 | CFT8634 | ||
CFT8634 is a degrader targeting BRD9. CFT8634 can be used for the research of synovial sarcoma and SMARCB1-deleted solid tumors. | |||
T79157 | Pimicotinib | ABSK021,ABSK-021 | c-Fms , Others |
Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors. | |||
T36395 | Trotabresib | CC-90010 | Epigenetic Reader Domain |
Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors. | |||
T9929 | Ramucirumab | VEGFR | |
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. | |||
T68144 | Spiroplatin | Others | |
Spiroplatin (TNO-6) is a novel platinum-containing analogue with antitumor activity that is commonly used in the study of solid tumors. | |||
T71137 | Simmitecan hydrochloride | Topoisomerase | |
Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors. | |||
T12433 | PF-06952229 | PF06952229 | TGF-beta/Smad |
PF-06952229 is a selective inhibitor of TGFβRI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer. | |||
T40199 | Tulmimetostat | CPI-0209 | Histone Methyltransferase |
Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced solid tumors. | |||
T2113 | PHA-793887 | PHA 793887,PHA793887 | Apoptosis , CDK |
PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors. | |||
T76706 | Varlilumab | CDX-1127 | TNF |
Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors. |